Medical Definition of Brittle bone disease

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Brittle bone disease: Osteogenesis imperfecta, not one but a group of genetic diseases, all of which affect collagen, a key component of connective tissue in tissues like bone, tendon and skin. All types of osteogenesis imperfecta result in fragile bones.

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Reviewed on 12/27/2018

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