Medical Definition of Endostatin

  • Medical Author:
    Melissa Conrad Stöppler, MD

    Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.

Endostatin: A fragment of a protein, collagen 18, that is found in all blood vessels. Endostatin is normally secreted by blood vessels in response to tumors. Endostatin appears to halt the process of developing new blood vessels (angiogenesis), which is necessary to tumor development.

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Reviewed on 12/27/2018

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