Medical Definition of Transaminase, serum glutamic pyruvic (SGPT)

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Reviewed on 12/27/2018

Transaminase, serum glutamic pyruvic (SGPT): An enzyme that is normally present in liver and heart cells, and is released into blood when the liver or heart is damaged. Blood SGPT levels are thus elevated with liver damage (for example, from viral hepatitis) or with an insult to the heart (for example, from a heart attack). Some medications can also raise SGPT levels. Interpretation of elevated SGPT levels depends on the context, and can necessitate additional clinical and laboratory information.

Also known as alanine aminotransferase (ALT).

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Reviewed on 12/27/2018