Y chromosome: The sex chromosome that is found, together with an X chromosome, in most normal males. The Y chromosome contains the unique male-determining gene and the male fitness genes that are active only in the testis and are responsible for the formation of sperm. Other genes on the Y chromosome have counterparts on the X chromosome, are active in many body tissues, and play crucial 'housekeeping' roles with the cell.
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Last Editorial Review: 6/9/2016