2005 ACR/ARHP Annual Scientific Meeting: Reports From National Arthritis Meeting
William Shiel, M.D., FACP, FACR, Editor of MedicineNet's Arthritis Overview, Offers Perspectives Of Interest On Topics From 2005 Annual Scientific Meeting of The American College of Rheumatology (held November 12-17, 2005)
Arthritis Conference - Installment #3 (transcript) on Lupus
Lupus (Systemic Lupus Erythematosus) Update
This is Dr. William Shiel, medical editor for Medicinenet.com reporting from the 2005 Annual Scientific Meeting of The American College of Rheumatology in San Diego California - the National Arthritis meeting. The topic I would like to discuss today is Systemic Lupus Erythematosus.
A very interesting paper was presented from Johns Hopkins school of medicine with authors Michele Petre et. al. relating to systemic lupus erythematosus . These researchers showed that when patients have blood abnormalities related to lupus as well as certain factors that indicate a tendency towards hypercoagulability -- which is a tendency of blood to clot with factors such as lupus anticoagulant and double stranded DNA antibodies for low serum complement. There is a strong association with kidney impairment in these lupus patients. It was also noted that Plaquenil which is the brand name for hydroxychloroquine may be protective in these patients. This is a very important paper because it tells doctors there's a method to managing kidney lupus or kidney disease in patients with lupus before it occurs. It was suggested by the authors of this research paper that treating the tendency towards blood clotting perhaps with blood thinners affecting certain parts of the blood system like using aspirin therapy or other methods to anticoagulant blood and using Plaquenil might decrease the chance for kidney lupus to occur. This is encouraging news for patients with lupus.
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