Medical Definition of Recombination

Recombination: The trading of fragments of genetic material between chromosomes before the egg and sperm cells are created. Key features of recombination include the point-to-point association of paired chromosomes (synapsis), followed by the visible exchange of segments (crossing over) at X-shaped crosspoints (chiasmata). Recombination is the principal way of creating genetic diversity between generations. Recombination ensures that children receive a different genetic makeup than their parents.

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Reviewed on 12/27/2018