Medical Definition of Propositus

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Propositus: The initial subject presenting a mental or physical disorder, who causes a study of his or her heredity in order to determine if other members of the family have had the same disease or carry it. Also called index case and proband.

Reviewed on 9/7/2018

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