Medical Definition of Pronucleus

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Pronucleus: A cell nucleus with a haploid set of chromosomes (23 chromosomes in humans) resulting from meiosis (germ-cell division). The male pronucleus is the sperm nucleus after it has entered the ovum at fertilization but before fusion with the female pronucleus. Similarly, the female pronucleus is the nucleus of the ovum before fusion with the male pronucleus.

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Reviewed on 12/27/2018

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