Medical Definition of Pancreatic insufficiency

Our Exocrine Pancreatic Insufficiency (EPI) Main Article provides a comprehensive look at the who, what, when and how of Exocrine Pancreatic Insufficiency (EPI)

Pancreatic insufficiency: Not enough of the digestive enzymes normally secreted by the pancreas into the intestine. Pancreatic insufficiency is a hallmark of cystic fibrosis.

Pancreas Illustration - Pancreatic insufficiency

The pancreas is a spongy, tube-shaped organ about 6 inches long. It is located in the back of the abdomen, behind the stomach. The head of the pancreas is on the right side of the abdomen. It is connected to the duodenum, the upper end of the small intestine. The narrow end of the pancreas, called the tail, extends to the left side of the body.

The pancreas makes pancreatic juices and hormones, including insulin. Pancreatic juices, also called enzymes, help digest food in the small intestine. Insulin controls the amount of sugar in the blood. Both enzymes and hormones are needed to keep the body working right.

As pancreatic juices are made, they flow into the main pancreatic duct. This duct joins the common bile duct, which connects the pancreas to the liver and the gallbladder. The common bile duct, which carries bile (a fluid that helps digest fat), connects to the small intestine near the stomach.

Quick GuideDigestive Disorders: Common Misconceptions

Digestive Disorders: Common Misconceptions

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Last Editorial Review: 6/9/2016

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