Medical Definition of Myeloproliferative disorders

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Myeloproliferative disorders: Malignant diseases of certain bone marrow cells including those that give rise to the red blood cells, the granulocytes (types of white blood cells), and the platelets (crucial to blood clotting).

The myeloproliferative disorders include myelophthisic anemia, erythroblastic leukemia, leukemoid reaction, myelofibrosis, myeloid metaplasia, polycythemia vera, and thrombocytosis. The myeloproliferative disorders are in contrast to the lymphoproliferative disorders which are malignancies of lymphoid cells and cells of the reticuloendothelial system (such as macrophages) which can take up inert particles and sequester them.

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Reviewed on 12/12/2018

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