Medical Definition of JC virus

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

JC virus: A virus that commonly causes infections of no consequence in children with a normal immune system, but which is responsible for an infection of the brain and spinal cord called progressive multifocal leukoencephalopathy (PML) in people with AIDS and other forms of immune system impairment. Abbreviated JVC. The JC virus is a human polyomavirus. It is a small virus with a closed circular genome consisting of double-stranded DNA. The letters JC are the initials of a patient with PML from whose brain the virus was first isolated.

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Reviewed on 12/21/2018

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