Rupture of appendix: A break or tear in the appendix, usually due to appendicitis. Also called perforation of the appendix. Rupture of appendix can lead to a periappendiceal abscess (a collection of infected pus) or diffuse peritonitis (infection of the entire lining of the abdomen and the pelvis). Also called perforation of the appendix.
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Reviewed on 12/21/2018