Medical Definition of Intervening sequence

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Reviewed on 12/12/2018

Intervening sequence: Part of a gene that is initially transcribed from the DNA into the primary RNA transcript but then is excised (removed) from it when the so-called exons sequences on either side of it are spliced together.

Intervening sequences, which are also called introns, are genetic sequences that intervene between the exons. The DNA of a gene is thereby made up of an alternation of introns and exons.

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Reviewed on 12/12/2018