Alkaptonuria

Take the Low Testosterone Quiz
Our Alkaptonuria Main Article provides a comprehensive look at the who, what, when and how of Alkaptonuria

Medical Definition of Alkaptonuria

Alkaptonuria: A genetic metabolic disorder due to deficiency of the enzyme homogentisic acid (HGA) dioxygenase. Deficiency of this enzyme leads to the three cardinal features of alkaptonuria (the presence of homogentisic acid in the urine), ochronosis (bluish-black pigmentation in connective tissue), and arthritis. Urine that turns dark is a characteristic feature.


Quick GuideScreening Tests Every Man Should Have

Screening Tests Every Man Should Have

Subscribe to MedicineNet's Men's Health Newsletter

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

Reviewed on 6/9/2016

Health Solutions From Our Sponsors