Medical Definition of BMPR1A

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

BMPR1A: A gene located on chromosome 10 in band 10q22.3 that encodes bone morphogenic protein receptor 1A, a kinase receptor that is involved in bone morphogenetic protein (BMP) signaling. Mutations in BMPR1A account for 25% to 40% of cases of juvenile polyposis, an autosomal dominant gastrointestinal polyposis syndrome in which patients are at risk for developing gastrointestinal cancers.

Reviewed on 9/7/2018

Health Solutions From Our Sponsors