Medical Definition of Guanine

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Guanine: One of the four bases in DNA that make up the letters ATGC. Guanine is the "G". The others are adenine, cytosine, and thymine. Guanine always pairs with cytosine to form the base pair G-C (guanine-cytosine) in the DNA. The other base pair in the DNA is A-T (adenine-thymine). Each base pair forms a rung in the DNA ladder. Guanine is also one of the four bases in RNA.

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Reviewed on 12/12/2018

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