Medical Definition of Upper motor neuron

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Upper motor neuron: A neuron that starts in the motor cortex of the brain and terminates within the medulla (another part of the brain) or within the spinal cord. Damage to upper motor neurons can result in spasticity and exaggerated reflexes. There is no standard laboratory test for upper motor neuron disease.

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Reviewed on 12/21/2018

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