Medical Definition of MCP1

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Reviewed on 12/21/2018

MCP1: Monocyte chemotactic protein-1, a member of the small inducible gene (SIG) family, plays a role in the recruitment of monocytes to sites of injury and infection. The gene for MCP1 is on chromosome 17 in region 17q11.2-q12.

MPC1 has been found in the joints of people with rheumatoid arthritis where may serve to recruit macrophages and perpetuate the inflammation in the joints. MPC1 has also been found elevated in the urine of people with lupus as a sign warning of inflammation of the kidney.

MCP1 has also been called small inducible cytokine A2 (SCYA2) and monocyte chemotactic and activating factor (MCAF).

QUESTION

What causes tooth decay? See Answer

Health Solutions From Our Sponsors

Reviewed on 12/21/2018