Medical Definition of Biochemical aspirin resistance

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Biochemical aspirin resistance: The inability of aspirin to produce an anticipated effect on one or more tests of platelet function, such as inhibiting the biosynthesis of thromboxane, inhibiting platelet aggregation, and causing a prolongation of the bleeding time. The rationale for this testing is the concern as to whether aspirin therapy can in a given patient help prevent a heart attack or stroke.

Reviewed on 9/7/2018

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