Medical Definition of Chaperone

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Chaperone: 1. Any protein that is required for the proper folding or assembly of another protein or protein complex without being a component of the final structure. 2. A woman who is present when a male physician examines a female patient. 3. Anyone present when a physician examines a patient of the opposite sex from the physician.

From the original meaning of chaperone as a person (usually a matron) who accompanied an unmarried woman in public or mixed company for the sake of propriety.

Reviewed on 9/7/2018

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