Medical Definition of Transdifferentiation

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Reviewed on 12/21/2018

Transdifferentiation: 1. The change of a cell or tissue from one differentiated state to another. 2. The differentiation of a tissue-specific stem cell into another type of cell as, for example, a bone marrow stem cell differentiating into a neuron.

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Reviewed on 12/21/2018