Medical Definition of Effect, founder

  • Medical Author:
    Melissa Conrad Stöppler, MD

    Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.

Effect, founder: The positive effect on gene frequency when a population (colony) has only a small number of original settlers, one or more of whom had that gene. For example, the gene for Huntington's disease was introduced into the Lake Maracaibo region in Venezuela early in the nineteenth century. This is now the largest known aggregation of the Huntington's gene in the world.

Reviewed on 9/7/2018

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