B-type natriuretic peptide: A 32-amino-acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells. The levels of B-type natriuretic peptide are elevated in patients with congestive heart failure, and correlate with both the severity of symptoms and the prognosis. Also known as BNP.
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Last Editorial Review: 5/13/2016