Medical Definition of Retroposition

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Reviewed on 12/21/2018

Retroposition: 1. Simple backward displacement of a structure or organ such as the uterus.
2. In genetics, the integration of a sequence derived from RNA into a DNA genome. Messenger RNA (mRNA) is reverse-transcribed and reintegrated into the genome. Retroposition is an important mechanism of gene copying. It produces a large number of functional genes in the genome and accounts for about 10,000 duplications in the human genome.

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Reviewed on 12/21/2018