Medical Definition of Gastric MALT lymphoma

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Gastric MALT lymphoma: A low-grade malignant lymphoma of the stomach associated with chronic infection by the bacterium H. pylori. Three-quarters of gastric MALT lymphomas regress after the eradication of H. pylori with antibiotics. The one-quarter that are unresponsive to antibiotics carry a characteristic chromosomal translocation or are at an advanced stage. The translocation is of the t(11;18)(q21;q21) type.

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Reviewed on 12/21/2018

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