Medical Definition of MIC-1

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

MIC-1: Macrophage inhibitory cytokine 1. MIC-1 is produced in the placenta. A divergent member of the transforming growth factor beta superfamily. There are detectable levels of MIC-1 in the blood of the mother during pregnancy. Low levels of MIC-1 in maternal serum are predictive for an elevated risk of early pregnancy loss. Also known as placental bone morphogenetic protein and placental BMP.

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Reviewed on 12/21/2018

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