Medical Definition of Bone morphogenic protein 2

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Bone morphogenetic protein 2: A protein that induces the formation of bone and cartilage. Bone morphogenic protein 2 (which is symbolized BMP2) belongs to a superfamily called transforming growth factor beta (TGF-beta). The gene for BMP2 is on chromosome 20 in band 20p12.3. Three sets of variations within the BMP2 gene reportedly triple the risk of developing osteoporosis.

See also: Bone morphogenetic protein; Osteoporosis.

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Reviewed on 12/21/2018

REFERENCE: NCBI.gov. BMP2 bone morphogenetic protein 2 [Homo sapiens].

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