Medical Definition of Protein kinase A

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Protein kinase A: An enzyme system that is activated by cyclic adenosine monophosphate (cAMP) and that catalyzes the activity of intracellular proteins. There are two isozymes of protein kinase A, type I and type II. Also known as cAMP-dependent protein kinase and cyclic AMP-dependent protein kinase.

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Reviewed on 12/21/2018

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