Medical Definition of Blot, Western

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Blot, Western: A technique in molecular biology that is used to separate and identify proteins. It is called a Western blot merely because it is similar to a Southern blot, which was named after its inventor, the British biologist M.E. Southern. For example, the Western blot assay method is commonly used to diagnose Lyme disease.

Reviewed on 9/7/2018

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