Medical Definition of West Nile virus

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

West Nile virus: The mosquito-borne virus that causes West Nile fever. One of the flaviviruses, a family of viruses also responsible for dengue, yellow fever, and tick-borne encephalitis virus. Like the other flaviviruses, the West Nile virus is a positive-strand RNA virus containing three structural proteins and a host-derived lipid bilayer. The West Nile virus is an icosahedral structure of about 500 angstroms in diameter. The overall structure of the West Nile virus most closely resembles that of dengue fever virus but the surface proteins are slightly different, which may give West Nile virus some of its unique features.

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Reviewed on 12/21/2018

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