Medical Definition of Enediyne

Enediyne: A very potent and naturally occurring antibiotic that acts by cleaving DNA. The adverse effects of enediynes on cells include mutagenicity (increase mutation), halting mitois (cell division) by arresting the cell cycle, and inducing apoptosis (programmed cell death). Enediynes were first isolated in the 1960s by the fermentation of microbes.

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Last Editorial Review: 6/9/2016

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