Medical Definition of Enediyne

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Enediyne: A very potent and naturally occurring antibiotic that acts by cleaving DNA. The adverse effects of enediynes on cells include mutagenicity (increase mutation), halting mitois (cell division) by arresting the cell cycle, and inducing apoptosis (programmed cell death). Enediynes were first isolated in the 1960s by the fermentation of microbes.

Reviewed on 9/7/2018

Health Solutions From Our Sponsors