Medical Definition of BP1

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

BP1: Beta protein 1, a protein encoded by a member of the homeobox gene family, a group of genes important to early development of the fetus. Specifically, BP1 belongs to the DLX homeobox family. BP1 acts as a transcription factor that turns other genes on and off and regulates the beta globin gene. BP1 is overexpressed in a large proportion of cases of acute myeloid leukemia (AML) and breast cancer.

Reviewed on 12/11/2018

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