Color-Changing Bandage Identifies and Treats Infections

What if you could detect and treat bacterial skin infections quickly with a bandage?
By on 02/14/2020 11:09 AM

Source: MedicineNet Health News

What if you could detect and treat bacterial skin infections quickly with a bandage? One day soon, you may be able to.

It's not sci-fi. Researchers from the Chinese Academy of Sciences have invented a bandage that changes color if a bacterial infection is present. And the color change also indicates whether the bacteria is resistant to antibiotics.

How does this magical bandage that detects and treats infections work? Scientists designed the paper-based bandage to remain green as long as a wound is not infected according to the study published in the journal, ACS Central Science.

The bandage turns yellow in the presence of bacteria due to the acidity that occurs with infection. The bandage then releases an antibiotic to quickly treat the infection.

If the bandage detects the presence of antibiotic-resistant bacteria, it turns red due to enzymes released at the infection site. Doctors can then shine a specific wavelength of light on the bandage to activate so-called "reactive oxygen species," unstable molecules that kill or weaken the bacteria, rendering it more susceptible to antibiotics.

The bandages have only been tested on mice so far, not people, according to the study. The bandages were successful at differentiating treatable bacterial infections from antibiotic-resistant infections and did speed wound healing of both kinds of bacterial infections.

Bacterial skin infections can usually be cured by antibiotics, according to MedicineNet author, . However, "Some bacteria have become resistant to the drugs and are harder to kill," she notes.

Methicillin-resistant Staphylococcus aureus (MRSA) is one type of antibiotic-resistant bacteria. It can cause skin abscesses that are difficult to treat, Dr. Pathak said. She notes that people in hospitals and nursing homes are most likely to get MRSA, as are those who have skin-to-skin contact with others, like child care workers and wrestlers.

Current methods to identify bacteria causing skin infections are time consuming and require the use of expensive instruments and medical personnel. Bandages that quickly diagnose and treat bacterial skin infections represent a much-needed time- and money-saving innovation.

MedicineNet author, , notes, "In many cases treatment decisions are needed before test results are known and healthcare providers may prescribe broad-spectrum antibiotics when a more specific treatment might be better." The ability to diagnose antibiotic-resistant bacterial skin infections quickly with color-changing bandages and the naked eye will allow for timely targeted treatment.

Accurate diagnosis of bacterial infections and appropriate use of antibiotics may help combat the growing issue of antibiotic resistance, Dr. Cunha said.

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