Medical Definition of Toll receptor

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Reviewed on 12/11/2018

Toll receptor: One of a family of receptors that provide a critical link between immune stimulants produced by microorganisms and the initiation of the host defense. Activation of the toll receptors causes the release of antimicrobial peptides, inflammatory cytokines, and molecules that initiate adaptive immunity.

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Reviewed on 12/11/2018