Medical Definition of Granuloma inguinale (donovanosis)

  • Medical Author:
    Melissa Conrad Stöppler, MD

    Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.

Granuloma inguinale (donovanosis): a sexually transmitted disease (STD) caused by the bacterium Klebsiella granulomatis (formerly known as Calymmatobacterium granulomatis). The disease produces slowly developing, painless ulcers on the genital organs that may bleed. Nodules beneath the skin in the affected area may be found. The condition is rare in the US, but is common in some developing areas of the world including India, New Guinea, and the Caribbean. The diagnosis of granuloma inguinale requires demonstration of the bacteria in a tissue sample. Granuloma inguinale is sometimes referred to as donovanosis.

Reviewed on 8/29/2018

REFERENCE: 2015 Sexually Transmitted Diseases Treatment Guidelines; Granuloma Inguinale (Donovanosis). CDC. Updated: Jun 04, 2015.

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