Latest Alzheimer's News
THURSDAY, July 5, 2018 (HealthDay News) -- If new research in mice bears out in humans, that daily low-dose aspirin many people take to keep heart trouble at bay might also protect their brains against Alzheimer's.
"The results of our study identifies a possible new role for one of the most widely used, common, over-the-counter medications in the world," said senior study author Kalipada Pahan, chair of neurology at Rush Medical College, in Chicago.
Previous research has shown a link between aspirin and a reduced risk of Alzheimer's disease. In this study, the scientists gave low-dose aspirin for a month to genetically modified mice with a form of Alzheimer's disease.
The aspirin helped reduce amyloid plaques by boosting a protein called TFEB, a regulator of waste removal, and by stimulating lysosomes, a part of cells that help clear waste. But not all research in animals holds true for humans.
"This research study adds another potential benefit to aspirin's already established uses for pain relief and for the treatment of cardiovascular diseases," he added in a Rush University news release.
"More research needs to be completed, but the findings of our study has major potential implications for the therapeutic use of aspirin in [Alzheimer's] and other dementia-related illnesses," Pahan said.
The study was published in the July issue of The Journal of Neuroscience.
-- Robert Preidt
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