Medical Definition of Ectodermal dysplasia

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Ectodermal dysplasia: A genetic disorder in which the skin and associated structures (the hair, nails, teeth, and sweat glands) develop abnormally. X-linked anhidrotic (nonsweating) ectodermal dysplasia is most common; because it is an X-linked trait, it mainly affects males. There is also an autosomal dominant form that affects both males and females. The term ectodermal dysplasia refers to the abnormal development (dysplasia) of structures derived from one of the germ cell layers in the embryo (ectoderm).

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Reviewed on 12/11/2018

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