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In the study, which covered the years from 1996 to 2015, investigators from Thomas Jefferson University in Philadelphia and the University of North Carolina analyzed data from a multi-institution database on 581 stage 2 melanoma patients who were followed for at least one year. Of those, 171 (29 percent) had a recurrence of their cancer.
Thirty percent were detected by scheduled doctor exams and 26 percent were spotted in routine imaging tests, according to the study published recently in the Journal of the American College of Surgeons.
"Patients need to be aware of all of their symptoms and their body. But it's also important for physicians to educate patients as to what to look for and what symptoms are a cause for concern," study co-author Dr. Adam Berger, a professor of surgery at Thomas Jefferson University, said in a journal news release.
"Patients should examine their skin and the area where lymph nodes would be on a monthly basis. And if they have a symptom that doesn't go away after two or three weeks, it should be brought to a physician's attention, because that is an indicator that the melanoma has come back," he said.
Berger added, "The fact that imaging picked up 26 percent of patients with recurrence is notable because it is a little higher than what we've seen in the past, which I think reflects the current trend to do more imaging in general. There is a move to use CT scans and other imaging techniques as an important strategy in early recurrence detection."
Melanoma has a 95 percent cure rate if caught and treated early, but some research suggests the recurrence rate for melanoma is as high as 50 percent, the study authors said.
"We are most concerned about patients who have stage 2 melanoma," Berger said. "They have more advanced primary melanomas and, on average, between 20 and 45 percent of these patients will die within five years. In the past, we didn't have good therapies for this type of melanoma, but new therapies mean survival continues to improve."
-- Robert Preidt
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