Medical Definition of Blue sclera

  • Medical Author:
    Melissa Conrad Stöppler, MD

    Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.

Blue sclera: a bluish coloration of the whites of the eyes. The blue color is caused by thinness and transparency of the collagen fibers of the sclera, allowing the veins in the underlying tissue to show through. Blue sclerae are characteristic of a number of conditions, particularly connective tissue disorders. These include osteogenesis imperfecta, Marfan's syndrome, Ehlers-Danlos syndrome, pseudoxanthoma elasticum, and Willems De Vries syndrome, among others.

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Last Editorial Review: 1/25/2017

REFERENCE: Walsh, S. "The Eyes Have It." Medscape.
<https://www.medscape.com/viewarticle/582177>

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