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THURSDAY, Sept. 29, 2016 (HealthDay News) -- Knowing they have a family history of breast cancer or a high-risk gene mutation doesn't lead to increased anxiety or depression in teen girls, a new study finds.
"Overall, girls in families with a history of breast cancer seem to cope pretty well over time," said study author Dr. Angela Bradbury. She is an assistant professor of hematology/oncology at the University of Pennsylvania's Abramson Cancer Center in Philadelphia.
"They do worry more about breast cancer than their peers do, particularly as they get older, but that doesn't seem to impact them in terms of depression, anxiety and general psychosocial adjustment," Bradbury explained in a university news release.
The study included 320 girls, aged 11 to 19. Of those girls, 208 were from families with a history of breast cancer or high-risk BRCA 1/2 mutations in close relatives. The other 112 were "controls" with no such family history.
Participants were interviewed to assess their mental health, perception of breast cancer risk, and levels of distress about breast cancer.
The investigators found that girls with a family history of breast cancer had higher levels of self-esteem.
"Self-esteem was higher among girls with a stronger family history of breast cancer, whereas depression was lower with increasing number of relatives with breast cancer," Bradbury said. "It may be that exposure to relatives with cancer fosters adaptive responses, although there may be other individual, mother, and family factors at work here."
The researchers are now investigating how increased concerns about breast cancer risk affect the behaviors of teen girls as they age, and whether they require help.
"If it's a harmful thing for a girl to know she's at risk, we need to know which girls are anxious and how we can help them, and if it's a beneficial thing, we need to know how best to capitalize on it," Bradbury said.
A 2015 study from the same research team revealed similar findings in girls aged 10 to 13.
The new study was published in the Oct. 1 print issue of the Journal of Clinical Oncology.
-- Robert Preidt
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