Medical Definition of Goodman syndrome

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Goodman syndrome: A genetic syndrome characterized by acrocephalosyndactyly -- birth defects involving the head and face and the fingers. The craniofacial features are essentially those of acrocephaly while the finger abnormalities include polydactyly (extra fingers), syndactyly (fusion of the fingers), clinodactyly, and ulnar deviation (with the fingers deviated laterally, toward the ulnar bone). The syndrome is inherited as an autosomal recessive trait (unlike most forms of acrocephalosyndactyly which are autosomal dominant traits).

The syndrome was described in 1979 by the pioneering American-Israeli medical geneticist Richard M. Goodman and his colleagues who called it acrocephalopolysyndactyly IV (ACPS IV). Today it is sometimes called Goodman syndrome.

Reviewed on 9/7/2018

Health Solutions From Our Sponsors