Medical Definition of GB virus C

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

GB virus C: A virus first identified in 1995 that is genetically related to the hepatitis C virus but which does not cause hepatitis and, in fact, is not known to be responsible for any disease.

Infection with GB virus C (GBV-C) is beneficial to HIV-infected patients. They enjoy longer survival if they are coinfected with this virus and HIV than if they have HIV alone. Having two viruses is better than one here. Having both HIV and GB virus C is better than having HIV alone.

GB virus C (GBV-C) is also called hepatitis G. However, the designation GB virus C (GBV-C) is preferred because the virus is not a cause of hepatitis.

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Last Editorial Review: 1/24/2017

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