Medical Definition of Becker muscular dystrophy

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Becker muscular dystrophy: A chronic, progressive muscle degeneration disease. A form of muscular dystrophy that is quite similar to Duchenne muscular dystrophy, except that patients with Becker do produce some of the key protein, dystrophin, whereas those with Duchenne do not. Progression of the disease in Becker type is slower than in Duchenne, and symptoms may appear as late as the mid-twenties.

Becker muscular dystrophy is a mild version of Duchenne. Both diseases result from mutations in the huge gene in region Xp21.2 on the X chromosome that encodes dystrophin. (The other principal form of X-linked, late-onset muscular dystrophy is Emery-Dreifuss muscular dystrophy, which results from mutation in the gene encoding emerin on Xq28.)

Last Editorial Review: 1/24/2017

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