Medical Definition of Q fever vaccine

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Q fever vaccine: A vaccine against Q fever, an illness first recognized in Australia in the 1930's that affects people dealing with infected sheep and cattle and their hides and carcasses.

The microscopic bacterial agent of Q fever, Coxiella burnetii, is spread with airborne dust and contaminated milk. It was named Q, for query, because little was clear about the condition except that it caused bad fevers, headaches, sweating, dry coughs and chest and muscle pain, normally lasting up to two weeks. The first outbreaks of Q fever in Europe affected troops from both sides in World War II, prompting a concentrated effort to search for a remedy.

An American microbiologist, Dr. Paul Fiset collaborated with Dr. Michael George Stoker at Cambridge University in England from 1953 to 1956 to decode the structure of Coxiella burnetii. Dr. Fiset's later studies (at the Universities of Rochester and Maryland) were instrumental in the creation of a vaccine for Q fever.

Reviewed on 12/11/2018

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