Latest HIV News
Gilead's Complera Joins Atripla as Only One-a-Day Complete HIV Treatments
By Daniel J. DeNoon
WebMD Health News
Reviewed by Laura J. Martin, MD
The first single-tablet regimen for HIV, Gilead's Atripla, was approved by the FDA in 2006. Yet another single-pill treatment from Gilead, the four-drug Quad, is in advanced clinical trials.
Complera is approved as a first-line treatment for adults with HIV infection who have not yet begun treatment with any other HIV medications.
It's not for everyone, as different doctors may prefer to prescribe different HIV drug combinations for different patients. However, the once-daily formulation makes it much easier for people to take their medication exactly as prescribed. That's extremely important for people with HIV, as the AIDS virus can quickly become resistant to HIV drugs when doses are missed.
Like all HIV drugs, Complera can have serious side effects. These include lactic acidosis and severe liver damage -- side effects linked to most drugs in the class of nucleoside reverse transcriptase inhibitors when given as part of combination therapy.
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