Medical Definition of Proteome

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Proteome: The complete set of proteins expressed and modified following their expression by the genome. The term "proteome" was coined from the PROTEin complement of the genOME in 1994 by Marc Wilkins, a graduate student at Macquarie University in Australia.

The analysis of the proteome is proteomics which Wilkins defined as "the study of proteins, how they're modified, when and where they're expressed, how they're involved in metabolic pathways and how they interact with one another."

Reviewed on 9/7/2018

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