Medical Definition of Angiomyxoma, aggressive

  • Medical Author:
    Melissa Conrad Stöppler, MD

    Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.

Angiomyxoma, aggressive: A slow-growing tumor of stromal cells which occurs primarily in the genital and pelvic regions. This tumor is much more common in women. It can range from relatively small tumors to football-size masses in the pelvis. The histologic appearance of the tumor under the microscope is rather distinctive.

Treatment consists of surgical excision (removal). Unfortunately, there is a relatively high rate of recurrence because the exact extent of the tumor is difficult for the surgeon to determine. These tumors appear not to have the ability to metastasize (spread to distant organs).

References:

Fishman-A; Aggressive angiomyxoma of the pelvis and perineum. A case report. J-Reprod-Med. 1995 Sep; 40(9): 665-9.

Fetsch JF; Aggressive angiomyxoma: a clinicopathologic study of 29 female patients. Cancer Vol. 78 no. 1 pp. 79-90.

Reviewed on 9/7/2018

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