Medical Definition of Tamoxifen (Nolvadex)

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Last Editorial Review: 1/24/2017

Tamoxifen (Nolvadex): An antiestrogen (a drug that blocks the effects of estrogen) which competes with estrogen for binding sites in target tissues such as breast.

Tamoxifen has been widely publicized. It was approved by the US Food and Drug Administration (FDA) to treat breast cancer and help prevent it in women at high risk for the disease and, then in 2000, to treat women who have had surgery and radiation for ductal carcinoma in situ (DCIS) to lower the risk of invasive breast cancer arising from the intraductal carcinoma.

QUESTION

A lump in the breast is almost always cancer. See Answer

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Last Editorial Review: 1/24/2017