Medical Definition of Wilms tumor

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Wilms tumor: A childhood form of kidney cancer with a peak age of occurrence at 3 years of age. It is sometimes associated with abnormalities of the urinary tracts or other birth defects. Some cases are related to defects in one of two genes referred to as Wilms' tumor 1 (WT1) or Wilms' tumor 2 (WT2). Symptoms can include abdominal pain, swelling, and blood in the urine. Diagnosis is made by biopsy, which can classify the tumors as having a favorable histology (microscopic appearance) or an unfavorable histology, which is associated with a worse outcome. The outcome is also reflected by the stage of the tumor (extent of spread) at the time of diagnosis. Treatment involves surgery and chemotherapy; sometimes radiation therapy is also recommended. Wilms tumor has a very high cure rate, particularly when detected as a localized tumor. Also known as nephroblastoma.

CONTINUE SCROLLING OR CLICK HERE FOR RELATED ARTICLE
Reviewed on 12/11/2018

Health Solutions From Our Sponsors