Medical Definition of Sarcoidosis

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Sarcoidosis: A disease of unknown origin that causes small lumps (granulomas) due to chronic inflammation in body tissues. Sarcoidosis can appear in almost any body organ, but it most often starts in the lungs or lymph nodes. It can also affect the eyes, liver, and skin; and less often it affects the spleen, bones, joints, skeletal muscles, heart, and central nervous system. In the majority of cases, the granulomas clear up with or without treatment. In cases where the granulomas do not heal and disappear, the tissues tend to remain inflamed and become scarred.

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Reviewed on 12/11/2018

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